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Thursday, May 7, 2020 | History

2 edition of Ethylene oxide technical report found in the catalog.

Ethylene oxide technical report

G. Briggs Phillips

Ethylene oxide technical report

1978 submission to the Environmental Protection Agency

by G. Briggs Phillips

  • 29 Want to read
  • 2 Currently reading

Published by Health Industry Manufacturers Association in Washington .
Written in English

    Places:
  • United States.
    • Subjects:
    • Ethylene oxide.,
    • Medical instruments and apparatus -- Sterilization.,
    • Medical supplies -- Sterilization.,
    • Ethylene oxide -- Safety regulations -- United States.,
    • Ethylene oxide -- Toxicology.

    • Edition Notes

      Includes bibliographies.

      Statementprepared by G. Briggs Phillips, Howard M. Holstein, Lawrence J. Worden.
      SeriesHIMA report ; 78-3, HIMA report ;, 78-3.
      ContributionsHolstein, Howard M., joint author., Worden, Lawrence J., joint author., United States. Environmental Protection Agency.
      Classifications
      LC ClassificationsRA766.E8 P44
      The Physical Object
      Pagination496 p. in various pagings :
      Number of Pages496
      ID Numbers
      Open LibraryOL4447426M
      LC Control Number79109467

      Ethylene oxide gas is an agent in the sterilization of medical devices due to its effectiveness and compatibility with most materials. The advantages and disadvantages, as well as its recommended. The CEFIC Ethylene Oxide and Derivatives Sector Group recommends that these Guidelines are adopted by all parties who are involved in the distribution of ethylene oxide, and will arrange a regular review of these guidelines. In order to facilitate effective supervision of safety in transport to destination, it is recommended that ethylene oxideFile Size: 1MB.

        Ethylene oxide: incident management Ref: PHE publications gateway number PDF, KB, 15 pages This file may not be suitable for users of assistive technology. High Purity Ethylene oxide (HPEO) is a colourless, highly reactive and flammable gas at room temperature. It is produced by direct oxidation of ethylene with air or oxygen. Because it reacts readily with other chemicals, HPEO is one of the most versatile intermediates and is used to produce many derivative products.

      Production of Ethylene and its Commercial Importance in the Global Market ity (%) at °C (Shi, Ji, Wang, & Li, ). The authors claimed that the hexagonal mesoporous. Other articles where Ethylene oxide is discussed: heterocyclic compound: Three-membered rings: oxygen, and sulfur—aziridine, oxirane (or ethylene oxide), and thiirane, respectively—and their derivatives can all be prepared by nucleophilic reactions, of the type shown. Thus, aziridine is formed by heating β-aminoethyl hydrogen sulfate with a base (in this case Y is ―OSO3H).


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Ethylene oxide technical report by G. Briggs Phillips Download PDF EPUB FB2

As a part of the chemical industry’s responsible management of its products, the Ethylene Oxide Panel Ethylene Oxide Safety Task Group (STG), a group comprised of producers and industrial users, developed the Ethylene Oxide Product Stewardship Manual – 3rd edition.

Ethylene oxide, called oxirane by IUPAC, is an organic compound with the formula C 2 H 4 is a cyclic ether and the simplest epoxide: a three-membered ring consisting of one oxygen atom and two carbon ne oxide is a colorless and flammable gas with a faintly sweet odor.

Because it is a strained ring, ethylene oxide easily participates in a number of addition reactions that Chemical formula: C₂H₄O. Learn about ethylene oxide, which can raise your risk of lymphoma and leukemia.

Exposure may occur through industrial emissions, tobacco smoke, and the use of products sterilized with ethylene oxide, such as certain medical products or cosmetics.

@article{osti_, title = {Health-hazard evaluation report HETAKendall Company, Augusta, Georgia. [Ethylene oxide]}, author = {Seligman, P and Gorman, R}, abstractNote = {Environmental and breathing-zone samples were analyzed for ethylene oxide at the Kendall Company, Augusta, Georgia in August, and July and August, @article{osti_, title = {Assessment of ethylene oxide concentrations and emissions from sterilization and fumigation processes.

Final report}, author = {Havlicek, S.C. and Hilpert, L.R. and Dai, G. and Pierotti, D.}, abstractNote = {Recent concern regarding the mutagenic and carcinogenic properties of ethylene oxide has created the need for the development of sensitive analytical.

Ethylene oxide (C₂H₄O) is a flammable gas with a somewhat sweet odor. Exposure to ethylene oxide may cause headache, nausea, vomiting, diarrhea, breathing difficulty, drowsiness, weakness, exhaustion, eye and skin burns, frostbite, and reproductive effects.

Workers may be harmed from exposure to ethylene oxide. Ethylene oxide is a flammable gas with a somewhat sweet odor. It dissolves easily in ne oxide is a man-made chemical that is used primarily to make ethylene glycol (a chemical used to make antifreeze and polyester).

A small amount (less than 1%) is used to control insects in some stored agricultural products and a very small amount is used in hospitals to sterilize medical.

Ethylene Oxide. Hazard Summary. The major use of ethylene oxide is as a chemical intermediate in the manufacture of ethylene glycol. Ethylene oxide is also used as a sterilizing agent for medical equipment and a fumigating agent for spices.

The acute (short-term) effects of ethylene oxide in humans consist mainly of central nervous. What is ethylene oxide. Ethylene oxide (EtO) is a flammable, colorless gas at temperatures above ºF ( ºC) that smells like ether at toxic levels. EtO is found in the production of solvents, antifreeze, textiles, detergents, adhesives, polyurethane foam, and pharmaceuticals.

Smaller amounts are present in fumigants, sterilants for spices. Ethylene oxide (also known as EO or EtO) is a low temperature gaseous process widely used to sterilize a variety of healthcare products, such as single-use medical devices.

Through the use of a vacuum-based process, EO sterilization can efficiently penetrate surfaces of most medical devices and its lower temperature makes it an ideal process.

The study, which is based both on desk research and multiple waves of qualitative primary research, is a must-read for entrepreneurs, investors, researchers, consultants, business strategists, and. The following references aid in recognizing and evaluating ethylene oxide hazards in the workplace.

Ethylene Oxide. OSHA Fact Sheet, (). Answers common questions regarding ethylene oxide. Ethylene Oxide (EtO): Evidence of Carcinogenicity.

National Institute for Occupational Safety and Health (NIOSH) Current Intelligence Bulle (May Technical Report No. 1: Validation of Moist Heat Sterilization Processes: Cycle Design, Development, Validation and Ongoing Control. 25 years of experience with drug and device sterilization with a variety of sterilization methods including moist heat.

Moerman, K. Mager, in Handbook of Hygiene Control in the Food Industry (Second Edition), Ethylene Oxide. Ethylene oxide (C 2 H 4 O), sometimes called oxirane, is an organic alkylating gas with very potent and highly penetrating properties.

Ethylene oxide is capable of destroying most viruses, bacteria, and fungi, including bacterial spores. Dirk W. Lachenmeier, in Side Effects of Drugs Annual, Ethylene Oxide [SED, ; SEDA, ; SEDA, ; SEDA, ]Ethylene oxide is used directly in the gaseous form to sterilize drugs, hospital equipment, disposable and reusable medical items, packaging materials, foods and other items [SEDA, ].A large number of samples of herbs, spices and other dried vegetables.

Save this Book to Read ethylene oxide product stewardship guidance manual PDF eBook at our Online Library. Get ethylene oxide product. Ethylene glycols (mono- di- triethylene glycol) constitute by far the single/largest outlet for ethylene oxide, accounting for about 73% of the EO market in Other dominant end uses include higher-value derivatives such as ethoxylates, ethanolamines, glycol ethers, polyethylene glycol, and polyether polyols.

Ethylene oxide (EtO) is a known carcinogen and mutagen associated with increased incidence of breast and blood cancers. The largest medical sterilization facility in Michigan had been assessed by the U.S.

Environmental Protection Agency as imposing an additional cancer risk greater than one in one thousand in nearby neighborhoods. This prompted the Michigan Department of Environmental Quality Author: Eduardo P. Olaguer, Amy Robinson, Susan Kilmer, James Haywood, Doreen Lehner. In spices, ethylene oxide at concentrations of 53 - mg/kg wet weight, measured 2 days after fumigation, fell to less than 25 mg/kg within another 24 days (Gerhardt & Ladd Effio, ).

Ethylene oxide will react with chloride and bromide ions in commodities to form 2-chloroethanol and 2-bromoethanol, respectively. PDA Education. East West Highway, Suite Bethesda, MD USA Tel: +1 () Fax: +1 (). Whether you are acquiring a new technology or responding to a rival, the ability to quickly compare technical designs and production costs is a competitive advantage.

For more than 50 years, the Process Economics Program (PEP) has provided in-depth, independent technical and economic evaluations of more than 1, commercial and emerging.The panel was created to promote the principles of Responsible Care ® with respect to the safe handling and use of ethylene oxide.

The Panel is actively involved in communicating on advocacy issues, current research, as well as educating government agencies and the public on health, safety and environmental issues arising from the production, use, storage, transportation and disposal of.used ethylene oxide as a sterilant (Norman et al.

). Studies on Mechanisms of Carcinogenesis Ethylene oxide is a direct-acting alkylating agent that forms adducts with biological macromolecules, including hemoglobin and DNA.

Ethylene oxide caused dose-related increases in the frequency of he-moglobin adducts in exposed humans and Size: KB.